Modern Poisons A Brief Introduction To Contemporary Toxicology Book PDF, EPUB Download & Read Online Free

Modern Poisons
Author: Alan Kolok
Publisher: Island Press
ISBN: 1610916093
Pages: 224
Year: 2016-05-05
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Traditional toxicology textbooks tend to be doorstops: tomes filled with important but seemingly abstract chemistry and biology. Meanwhile, magazine and journal articles introduce students to timely topics such as BPA and endocrine disruption or the carcinogenic effects of pesticides, but don't provide the fundamentals needed to understand the science of toxicity. Written by a longtime professor of toxicology, Modern Poisons bridges this gap. This accessible book explains basic principles in plain language while illuminating the most important issues in contemporary toxicology. Kolok begins by exploring age-old precepts of the field such as the dose-response relationship and the concept, first introduced by Ambroise Paré in the sixteenth century, that a chemical's particular action depends on its inherent chemical nature. The author goes on to show exactly how chemicals enter the body and elicit their toxic effect, as well as the body's methods of defense. With the fundamentals established, Kolok digs into advances in toxicology, tracing the field's development from World War II to the present day. The book examines both technical discoveries and their impacts on public policy. Highlights include studies of endocrine-disrupting chemicals in toiletries and prescriptions, the emerging science on prions, and our growing understanding of epigenetics. Readers learnnot only how toxic exposure affects people and wildlife, but about the long-term social and environmental consequences of our chemicals. Whether studying toxicology itself, public health, or environmental science, readers will develop a core understanding of—and curiosity about—this fast-changing field.
Understanding Toxicology
Author: Steven Mercurio
Publisher: Jones & Bartlett Learning
ISBN: 1284127613
Pages: 952
Year: 2016-08-30
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Understanding Toxicology is a comprehensive study of toxicants and their impact on all levels of biology--from cell, to complex organism, to ecosystem. Unlike other texts of its kind, this text is uniquely structured by biological system, making it easy for readers to understand the impact of toxins on each system. Common mechanisms are explored in the cellular and complex organ system chapters to approach a systems biology perspective that is more applicable to modern computational toxicology risk assessment. Understanding Toxicology begins with three research questions that challenge the reader to discover what information is needed to solve controversies at the level of the cell, the complex organism, and the ecosystem. The book continues with a cellular, complex organism, and ecosystem analysis of toxicology principles including risk assessment. The cellular section follows common mechanisms from the outside to the inside of cells and individual organelles. A forensic approach analyzes complex organisms from outside to inside. The ecosystem section starts with a dispersion approach to determine environmental concentration and addresses toxicants in divisions similar to how the EPA determines impacts. Key Features • Uses lively, engaging examples making the text fun and easy to read and understand • Allows the reader to approach the subject from a research perspective as well as a public policy perspective • Covers biological toxicants including venoms, poisons, as well as microbial and fungal toxins, and plant toxins • Thoroughly covers all organisms including fish, plants, and microbes • Includes outlines and review questions in each chapter
Criminology of Homicidal Poisoning
Author: Michael Farrell
Publisher: Springer
ISBN: 3319591177
Pages: 209
Year: 2017-06-24
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This book provides an overview of historical and contemporary cases of homicidal poisoning. While homicidal poisoning is sometimes thought of as a thing of the past, it continues to be a contemporary problem, and in fact the unknown offender rate for poisoning cases is 20-30 times that of other homicide types in contemporary research, and many poisoners commit serial homicides while going undetected. The author of this important and timely work explores the theoretical bases for understanding homicidal poisoning, the nature of poisons used in homicidal cases, the characteristics of poisoners and their victims, and techniques for detection and prevention. This unique book will be of particular interest to: students of criminology (classes dealing with criminal psychology, and murder investigation); students of the history of crime; criminal justice professionals: attorneys, homicide detectives, forensic pathologists, forensic and clinical toxicologists, and other forensic investigators; and all interested in poisons, poisoners and the detection of poisoning. It has relevance to criminology, law and policing, toxicology and forensic science, the history of crime and detection, and criminal psychology.
Molecular and Biochemical Toxicology
Author: Robert C. Smart, Ernest Hodgson
Publisher: John Wiley & Sons
ISBN: 1119042410
Pages: 1040
Year: 2018-01-04
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Written as an advanced text for toxicology students, this book is much more than an introduction and provides in-depth information describing the underlying mechanisms through which toxicants produce their adverse responses. • Links traditional toxicology to modern molecular techniques, important for teaching to graduate courses and professional studies • Uses a didactic approach with basic biological or theoretical background for the methodology presented • Brings together and comprehensively covers a range of dynamic aspects in biochemical and molecular toxicology • Guides student and professional toxicologists in comprehending a broad range of issues, compiled and authored by a diverse group of experts • “A good introductory textbook covering the biochemical toxicology of organic substances and the relevant methodology in some detail.... It offers good value for money and can be recommended as a textbook for appropriate courses” – BTS Newsletter review of the 4th edition
Clarke's Analytical Forensic Toxicology
Author: Gail Cooper, Adam Negrusz
Publisher: Pharmaceutical Press
ISBN: 0857110543
Pages: 656
Year: 2013-05-28
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Clarke's Analytical Forensic Toxicology offers a fresh perspective on the drugs and poisons that are most likely to be encountered in forensic toxicology. It focuses on collection, extraction and analysis. This second edition is fully updated to reflect advances in analytical and forensic toxicology. New and extended chapters include: sampling, storage and stability; in-utero exposure to drugs of abuse; drug-facilitated sexual assault; extraction. Additional features are included from the fourth edition of Clarke's Analysis of Drugs and Poisons.
Medical Toxicology: Antidotes and Anecdotes
Author: Steven M. Marcus
Publisher: Springer
ISBN: 3319510290
Pages: 146
Year: 2017-02-23
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A collection of challenging and unusual cases from the author's extensive experience as a Medical Toxicologist, these cases demonstrate medical problem solving and differential diagnosis in action from the perspective of an experienced clinician. Written in an engaging style and giving a fascinating account of some complex cases from real practice, this book will provide a good supplementary learning text for graduate students or those at an early stage in their professional career.
More Molecules of Murder
Author: John Emsley
Publisher: Royal Society of Chemistry
ISBN: 1788011031
Pages: 272
Year: 2017-06-23
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How can a plant as beautiful as the foxglove be so deadly and yet for more than a century be used to treat heart disease? The same is true of other naturally occurring molecules as will be revealed in this current book by award-winning author and chemist, John Emsley. More Molecules of Murder follows on from his highly-acclaimed earlier book Molecules of Murder, and again it deals with 14 potential poisons; seven of which are man-made and seven of which are natural. It investigates the crimes committed with them, not from the point of view of the murderers, their victims, or the detectives, but from the poison used. In so doing it throws new light on how these crimes were carried out and ultimately how the perpetrators were uncovered and brought to justice. Each chapter starts by looking at the target molecule itself, its discovery, its chemistry, its often-surprising use in medicine, its effects on the human body, and its toxicology. The rest of the chapter is devoted to murders and attempted murders in which it has been used. But, be reassured that murder by poison is not the threat it once was, thanks to laws which restrict access to such materials and to the skills of analytical chemists in detecting their presence in incredibly tiny amounts.
Energy Efficiency
Author: James Sweeney
Publisher: Hoover Press
ISBN: 0817919562
Pages: 218
Year: 2016-08-01
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The entire world, especially the United States, is in the midst of an energy revolution. Since the oil embargo of 1973, individuals, corporations, and other organizations have found ways to economically reduce energy use. In this book, Jim Sweeney examines the energy policies and practices of the past forty years and their impact on three crucial systems: the economy, the environment, and national security. He shows how energy-efficiency contributions to the country's overall energy situation have been more powerful than all the increases in the domestic production of oil, gas, coal, geothermal energy, nuclear power, solar power, wind power, and biofuels. The author details the impact of new and improved energy-efficient technologies, the environmental and national security benefits of energy efficiency, ways to amplify energy efficiency, and more. Energy Efficiency: Building a Clean, Secure Economy reveals how the careful nurturing of private- and public-sector energy efficiency--along with public awareness, appropriate pricing, appropriate policies--and increased research and development, the trends of decreasing energy intensity and increasing energy efficiency can be beneficially accelerated.
Struggling for Air
Author: Jack Lienke
Publisher: Oxford University Press
ISBN: 0190233117
Pages: 232
Year: 2016-01-11
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Since the beginning of the Obama Administration, conservative politicians have railed against the President's "War on Coal." As evidence of this supposed siege, they point to a series of rules issued by the Environmental Protection Agency that aim to slash air pollution from the nation's power sector . Because coal produces far more pollution than any other major energy source, these rules are expected to further reduce its already shrinking share of the electricity market in favor of cleaner options like natural gas and solar power. But the EPA's policies are hardly the "unprecedented regulatory assault " that opponents make them out to be. Instead, they are merely the latest chapter in a multi-decade struggle to overcome a tragic flaw in our nation's most important environmental law. In 1970, Congress passed the Clean Air Act, which had the remarkably ambitious goal of eliminating essentially all air pollution that posed a threat to public health or welfare. But there was a problem: for some of the most common pollutants, Congress empowered the EPA to set emission limits only for newly constructed industrial facilities, most notably power plants. Existing plants, by contrast, would be largely exempt from direct federal regulation-a regulatory practice known as "grandfathering." What lawmakers didn't anticipate was that imposing costly requirements on new plants while giving existing ones a pass would simply encourage those old plants to stay in business much longer than originally planned. Since 1970, the core problems of U.S. environmental policy have flowed inexorably from the smokestacks of these coal-fired clunkers, which continue to pollute at far higher rates than their younger peers. In Struggling for Air, Richard L. Revesz and Jack Lienke chronicle the political compromises that gave rise to grandfathering, its deadly consequences, and the repeated attempts-by presidential administrations of both parties-to make things right.
An Introduction to Environmental Toxicology Second Edition
Author: Michael H. Dong
Publisher: Createspace Independent Pub
ISBN: 1477666486
Pages: 500
Year: 2012-08-01
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An Introduction to Environmental Toxicology Second Edition, like the first (student) edition, provides a general introductory text on the basic concepts of and general principles for environmental toxicology. To this end, the book is organized into 23 chapters in four parts:I. Toxicologic Concepts and Environmental Concerns (Chapters 1 – 5);II. Bioaccumulation and Biodisposition of Toxicants (Chapters 6 – 10);III. Nature and Effects of Environmental Toxicants (Chapters 11 – 17); andIV. General Considerations and Special Foci (Chapters 18 – 23).The book is an introduction to the basic principles, concepts, and issues for and of environmental toxicology intended for undergraduates majoring in environmental toxicology, environmental sciences, or a related field, as well as for graduate students taking a course in environmental toxicology as an elective. The book is also intended as a supplementary reading material for students whose instructor prefers to use her/his own lecture notes as text materials for their course. Students using this book are expected to have already completed a course in general biology and a course in general chemistry.The book is written as a primer covering lecture materials for a course of 3 to 6 semester units. The 23 chapters, totaling more than 450 pages, are arranged in a way that the reader is provided with the best flow and mode of comprehension, with each chapter including a set of review questions. Listed below are the chapter titles: 1. Scope and Principles for Environmental Toxicology 2. Environmental Changes and Environmental Health 3. Environmental Pollution and Regulatory Agencies 4. Occurrence and Types of Environmental Toxicants 5. Fate and Transport of Toxicants in the Environment 6. Bioaccumulation of Persistent Environmental Toxicants 7. Uptake and Distribution of Toxicants 8. Metabolism/Biotransformation of Xenobiotics 9. Adverse Action/Toxic Response10. Factors and Conditions Affecting Toxicity11. Air Pollutants – I. Inorganic Gases12. Air Pollutants – II. Particulate Matter13. Volatile Organic Compounds14. Toxic and Radioactive Metals15. Pesticides and Pesticide Residues16. Persistent Toxic Substances17. Biological and Physical Toxic Agents18. Environmental Mutagenesis/Carcinogenesis19. Reproductive Toxicity and Endocrine Disruption20. Industrial Chemicals/Occupational Toxicology21. Food Toxicants/Toxic Household Substances22. Human Health Aspects of Ecotoxicology23. Environmental Health Risk Assessment
Toxicology of Organophosphate and Carbamate Compounds
Author: Ramesh C. Gupta
Publisher: Academic Press
ISBN: 0080543103
Pages: 768
Year: 2011-04-28
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This text/reference book provides the most comprehensive coverage of anticholinesterase compounds (Organophosphates and Carbamates), which constitute the largest number of chemicals that are primarily used as insecticides in agriculture, industry, and around the home/garden. Some OPs (nerve agents) have been used in chemical warfare and terrorist attacks, while some OPs and CMs have been recommended as therapeutic agents in human medicine as well as in veterinary medicine. Many chemicals of both classes are extremely toxic and lack selectivity, thus their inadvertent/accidental use continues to pose a threat to human and animal health, aquatic systems and wildlife. These anticholinesterase agents produce a variety of toxicological effects in target and nontarget organs. In light of this complexicity, this multi-authored book is written by the well known scientists from many countries. The book is organized into nine sections, with a total of 49 chapters, to provide in-depth knowledge on various aspects of OP and CM compounds, including their use, classification, mechanism-based toxicity, and prophylactic and therapeutic measurements. Several chapters are written with special emphasis to cover timely topics, such as chemical warfare agents, physiologically-based pharmacokinetic modeling, structure and function of cholinesterases, paraoxonase, carboxylesterases; developmental neurotoxicity, the intermediate syndrome, oxidative stress, endocrine disruption, and DNA damage/gene expression and carcinogenesis. Section-VI with 5 chapters is specifically devoted to risk assessment, and safety and regulatory guidelines for pesticides. Describes everything you need to know about Organophosphates and Carbamates Extensively covers pesticides, nerve agents, therapeutic drugs, and flame retardants Describes epidemiology of the world's major disasters involving Organophosphates and Carbamates Covers animal, human, aquatic, and wildlife toxicity of Anticholinesterases Insights into in-depth cholinergic and noncholinergic mechanisms of toxicity Describes recent advancements in cholinesterases, paraoxonases, carboxylesterases, oxidative stress, endocrine disruption, cardiac and pulmonary toxicity, and carcinogenesis Provides in vitro and in vivo models for neurotoxicity testing Integrates knowledge of studies in lab animals and humans Offers risk/safety assessment and national/international guidelines for permissible levels of pesticide residues Describes management of Anticholinesterase poisoning in humans
Environmental Chemistry, Tenth Edition
Author: Stanley Manahan
Publisher: CRC Press
ISBN: 1498776949
Pages: 784
Year: 2017-02-24
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With clear explanations, real-world examples and updated questions and answers, the tenth edition of Environmental Chemistry emphasizes the concepts essential to the practice of environmental science, technology and chemistry while introducing the newest innovations in the field. The author follows the general format and organization popular in preceding editions, including an approach based upon the five environmental spheres and the relationship of environmental chemistry to the key concepts of sustainability, industrial ecology and green chemistry. This readily adaptable text has been revamped to emphasize important topics such as the world water crisis. It details global climate change to a greater degree than previous editions, underlining the importance of abundant renewable energy in minimizing human influences on climate. Environmental Chemistry is designed for a wide range of graduate and undergraduate courses in environmental chemistry, environmental science and sustainability as well as serving as a general reference work for professionals in the environmental sciences and engineering.
Legally Poisoned
Author: Carl F. Cranor
Publisher: Harvard University Press
ISBN: 0674058925
Pages: 328
Year: 2011-02-15
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Take a random walk through your life and you’ll find it is awash in industrial, often toxic, chemicals. Sip water from a plastic bottle and ingest bisphenol A. Prepare dinner in a non-stick frying pan or wear a layer of Gore-Tex only to be exposed to perfluorinated compounds. Hang curtains, clip your baby into a car seat, watch television—all are manufactured with brominated flame-retardants. Cosmetic ingredients, industrial chemicals, pesticides, and other compounds enter our bodies and remain briefly or permanently. Far too many suspected toxic hazards are unleashed every day that affect the development and function of our brain, immune system, reproductive organs, or hormones. But no public health law requires product testing of most chemical compounds before they enter the market. If products are deemed dangerous, toxicants must be forcibly reduced or removed—but only after harm has been done. In this scientifically rigorous legal analysis, Carl Cranor argues that just as pharmaceuticals and pesticides cannot be sold without pre-market testing, other chemical products should be subject to the same safety measures. Cranor shows, in terrifying detail, what risks we run, and that it is entirely possible to design a less dangerous commercial world.
Handbook of Toxicology of Chemical Warfare Agents
Author: Ramesh C. Gupta
Publisher: Academic Press
ISBN: 0128004940
Pages: 1198
Year: 2015-01-21
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Handbook of Toxicology of Chemical Warfare Agents, Second Edition covers every aspect of deadly toxic chemicals used in conflicts, warfare and terrorism. Including findings from experimental as well as clinical studies, this essential reference offers in-depth coverage of individual toxicants, target organ toxicity, major incidents, toxic effects in humans, animals and wildlife, biosensors and biomarkers, on-site and laboratory analytical methods, decontamination and detoxification procedures, and countermeasures. Expanding on the ground-breaking first edition, Handbook of Toxicology of Chemical Warfare Agents has been completely updated, presenting the most recent advances in field. Brand new chapters include a case study of the Iran-Iraq war, an overview of chemical weapons of mass destruction, explosives, ricin, the human respiratory system, alternative testing methods, brain injuries, and more. Unites world-leading experts to present cutting-edge, agent-specific information on chemical warfare agents and their adverse effects on human and animal health and the environment. Covers all aspects of chemical warfare agent modes of action, detection, prevention, therapeutic treatment and countermeasures. Features a full update on the first edition to reflect the most recent advances in the field as well as nine new chapters.
Casarett & Doull's Essentials of Toxicology, Third Edition
Author: John B. Watkins III, Curtis Klaassen
Publisher: McGraw-Hill Education / Medical
ISBN: 0071847081
Pages: 544
Year: 2015-08-17
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Understand the essential principles of toxicology and how poisons affect the human body with this accessible and engaging summary General Principles of Toxicology Disposition of Toxicants Nonorgan-directed Toxicity Target Organ Toxicity Toxic Agents Environmental Toxicology Applications of Toxicology Casarett & Doull’s Essentials of Toxicology is an easy-to-absorb distillation of the major principles and concepts that were presented in depth in Casarett & Doull’s Toxicology: The Basic Science of Poisons, Eighth Edition, the field’s gold-standard text. Presented in full color, the book concisely describes the science of toxicology, and includes important concepts from anatomy, physiology, and biochemistry to facilitate the understanding of the principles and mechanisms of toxicant action on specific organ systems. A summary of key points at the beginning and review questions at the end of each chapter help you study, understand, and memorize the material. Reflecting the expertise of more than sixty renowned contributors, Casarett & Doull’s Essentials of Toxicology is logically divided into seven sections: Succinct and comprehensive, there is no better text for gaining an understanding of essential principles, toxicokinetics, how toxic effects are passed on to succeeding generations, how each body system responds to poisons, and the specific effects of a wide range of toxic agents than Casarett & Doull’s Essentials of Toxicology.